Hemophilia is a pathology with unfavorable outcome, with high incidence of locomotor disabilities, which need an expensive treatment. Health status in chilhood has direct consequences in socio-economic status of adulthood. There is a bi-directional relation between psycho-socio-economic status and health state in hemophilia patient. Objective
During this study we proposed to estimate the impact of hemophilia on psychological and socio-economical status of the patient. Material For this study were enrolled 216 PwH hospitalised in Third Clinic of Pediatrics Timişoara and Clinical Center for Evaluation and Rehabilitation “Cristian Şerban” Buziaş, during the period december 2008 – may 2009:186 patients with hemophilia A and 30 patients with hemophilia B, < 18 years – 95 patients and >18 years -121. Method
Our study group was clinico-biologically analysed, and for self-assessment of current general health was used the questionnaire EQ5D (European Quality of Life-5 Dimensions). Also, the presence of other psychological disorders and social impact were estimated. Results
Those under the age 18-21,05% had pain on motion, vs the group >18 years, 66.92% with persistent pain. According to number of hemorrhages in last 6 months in <18 years group 21,05% had over 10 hemorrhages vs >18 years – 57,45%. Total joint score was 18,03±19,4in children and 35,52±21,73in adults. We assessed QOL using EQ;5D questionnaire. Age impacted all EQ;5D domains, as in severity influence, except anxiety and depression. Significant differences were observed in mobility, pain domains, in VAS and descriptive utilities, related to socio-professional status. Patients treated exclusively in HCC had better scores in all EQ;5D domains; significant differences were noticed in VAS. According to social insertion, only 35,13% among adults were employed. Deficiency in health status was reported in 29% of toddlers, 60% in group 6-9 age, ~70% in pre-adolescents and 75% adolescents group. Regarding adult category, deficiency was reported in 45,8%, disability in 27% and 12,3% were handicapped and needed social support. Conclusions
Hemophilia has unfavourable consequences on patient due the disabilities that occur during the evolution of the disease.